CORRECTED-UPDATE 1-Animal tests validate Novavax flu vaccine
* Vaccine protected ferrets against H1N1
* Even low doses of vaccine worked
(Corrects last paragraph to show the U.S. will produce 20 million doses of vaccine a week after mid-October, not per month)
By Maggie Fox, Health and Science Editor
The company said it made the vaccine, which uses so-called virus-like particles, in fewer than four weeks after the U.S. Centers for Disease Control and Prevention released the genetic sequence of the H1N1 swine flu virus, which is now causing a pandemic.
These virus-like particles are a mock version of the virus, made using the genetic sequence.
Novavax said the vaccine protected ferrets against the new pandemic strain. Ferrets are the closest animal to humans when it comes to being infected with influenza.
"The ferrets received a 3.75, 7.5, or 15 microgram dose of the 2009 H1N1 virus-like particle vaccine or a placebo and were boosted with a second dose after three weeks," the company said in a statement.
Researchers at the CDC infected the animals with H1N1 taken from a California patient. "By day five after challenge, immunized ferrets at all vaccine dose levels had cleared the H1N1 virus and showed no sign of disease," the company said.
"In contrast, control animals that received no vaccine displayed lethargy, elevated body temperatures and shed infectious virus for up to six days post-infection," it added.
Novavax would have to get U.S. Food and Drug Administration approval before it could test its new vaccine in people. Years of testing are likely to be required before such a new formulation of a vaccine could be widely used in people.
OLD FASHIONED TECHNOLOGY
Clinical trials of H1N1 vaccine made the old-fashioned way, with chicken eggs, are under way, and five companies are making it for the U.S. market -- AstraZeneca's (AZN.L: Quote, Profile, Research, Stock Buzz) MedImmune unit, CSL, GlaxoSmithKline Plc (GSK.L: Quote, Profile, Research, Stock Buzz), Novartis AG (NOVN.VX: Quote, Profile, Research, Stock Buzz) and Sanofi-Aventis SA (SASY.PA: Quote, Profile, Research, Stock Buzz).
Novavax Inc., based in Rockville, Maryland, has been using its new technology to develop a vaccine against H5N1 avian influenza.
Most influenza vaccines use either a weakened but live flu virus or a killed virus to stimulate the immune system. They must be reformulated every year to match the constantly mutating flu strains and take five to six months to make using specially grown live chicken eggs.
Novavax grows the vaccine in lab dishes of caterpillar cells in a process the company says is quicker. It uses a decoy of the virus called a virus-like particle. The body recognizes the particle as a virus but it cannot infect cells and replicate.
The World Health Organization declared H1N1 a pandemic in June, and the virus has spread to about 180 countries. World health officials have said people should receive the two-dose swine flu vaccination as well as the single-dose seasonal flu vaccination this year.
In July, U.S. advisers said about half the U.S. population, or 160 million people, should get vaccinated against the new pandemic influenza strain, with pregnant women and healthcare workers at the front of the line.
But the U.S. Health and Human Services Department has said it can only get about 45 million doses of flu vaccine by mid-October, and about 20 million doses a week after that.
AND TAKE A LOOK AT THIS LAWSUIT! The doctors mentioned in the video below are implicated.
Now this is getting interesting:
Follow the sequence:
The US announces that they will be SHORT OF VACCINE, THAT THE VACCINE WILL BE LATE.
Within 24 hours, they mention A NEW VACCINE, that SOMEHOW HAPPENED TO HAVE BEEN DEVELOPED IN THE US, IN MARYLAND, BY CDC SCIENTISTS, AND JUST ON TIME. COULD THERE BE A LINK THERE? IS THIS COMPANY GOING TO FILL THE VOID, AND MAKE MILLIONS OF DOLLARS FOR THE SAID CDC SCIENTISTS? COULD DR. HOROWITZ BE RIGHT? AFTER ALL, UNTIL NOW, WE HAD NOT REALLY HEARD OF NOVOVAX, EXCEPT FOR WHAT HE TOLD US.
NOW,ALL OF A SUDDEN, VERY CONVENIENTLY, THEY ARE MENTIONED, JUST ON TIME TO FILL THE HIGHLY PUBLICIZED VOID.
it matter not which vaccine one takes... from which company of manufacture... they will all kill u... plain and simple... also the scare tactics here are unmistakable... "oh my G-d... there won't be enough vaccine for everyone... i better run out right now and get mine asap..." etc. just to push people into compliance with their nazi-dictates... i hate these people involved in duping human beings into killing their own children and committing suicide themselves while doing so... i wish i could... nevermind... don't take the vaccine and if they make u go to jail or leave the country... nik. out...
WILL THEIR LICENSE BE SPED UP BY ' MIRACLE'???